![]() For kyphoscoliosis patients, again, we need more information on sleep as the thoracic deformity changes. Long-term evaluation of sleep and breathing in interstitial lung disease will give further insight into whether or not sleep changes are primary or secondary events. ![]() Changes in sleep architecture are likely related to the progression of the disease, but this is not known with certainty. As fibrotic lung disease progresses, the degree of nocturnal desaturation and breathing dysrhythmias will progress. For patients with interstitial lung disease, the role of nocturnal oxygen in chronic established fibrosis, and also in acute alveolitis (e.g., farmer's lung, bird fancier's lung, etc.), has not been addressed. The sleep literature is still sparse in most restrictive diseases. ![]() The combination of degree of restriction, whether it is intrapulmonary or extrapulmonary, and confounding factors, such as obesity, age, and sex, will ultimately determine the degree of disturbed nocturnal physiology. Restrictive lung disease patients exhibit a wide range of breathing and oxygenation abnormalities during sleep.
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